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  <xsd:element name="WarrantsToPurchaseClassACommonStockMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_WarrantsToPurchaseClassACommonStockMember" substitutionGroup="xbrli:item" />
  <xsd:element name="CustomerWarrantsMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_CustomerWarrantsMember" substitutionGroup="xbrli:item" />
  <xsd:element name="ClassOfInvestorsAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_ClassOfInvestorsAxis" substitutionGroup="xbrldt:dimensionItem" />
  <xsd:element name="ClassOfInvestorsDomain" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_ClassOfInvestorsDomain" substitutionGroup="xbrli:item" />
  <xsd:element name="ClassOfWarrantOrRightGrandDateFairValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" nillable="true" id="rgti_ClassOfWarrantOrRightGrandDateFairValue" substitutionGroup="xbrli:item" xbrli:balance="debit" />
  <xsd:element name="StatusOfVestingAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_StatusOfVestingAxis" substitutionGroup="xbrldt:dimensionItem" />
  <xsd:element name="StatusOfVestingDomain" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_StatusOfVestingDomain" substitutionGroup="xbrli:item" />
  <xsd:element name="VestedCustomerWarrantsMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_VestedCustomerWarrantsMember" substitutionGroup="xbrli:item" />
  <xsd:element name="UnvestedCustomerWarrantsMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_UnvestedCustomerWarrantsMember" substitutionGroup="xbrli:item" />
  <xsd:element name="ContingentEarnOutLiabilityMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_ContingentEarnOutLiabilityMember" substitutionGroup="xbrli:item" />
  <xsd:element name="ContingentEarnOutLiabilityFairValueDisclosure" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" nillable="true" id="rgti_ContingentEarnOutLiabilityFairValueDisclosure" substitutionGroup="xbrli:item" xbrli:balance="credit" />
  <xsd:element name="DerivativeWarrantLiabilitiesMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_DerivativeWarrantLiabilitiesMember" substitutionGroup="xbrli:item" />
  <xsd:element name="ScheduleOfShareBasedCompensationRestrictedStockAndRestrictedStockUnitsActivityAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_ScheduleOfShareBasedCompensationRestrictedStockAndRestrictedStockUnitsActivityAbstract" substitutionGroup="xbrli:item" />
  <xsd:element name="RestrictedStockUnitsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_RestrictedStockUnitsTable" substitutionGroup="xbrldt:hypercubeItem" />
  <xsd:element name="ScheduleOfShareBasedCompensationRestrictedStockAndRestrictedStockUnitsActivityLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_ScheduleOfShareBasedCompensationRestrictedStockAndRestrictedStockUnitsActivityLineItems" substitutionGroup="xbrli:item" />
  <xsd:element name="TimeBasedVestingAwardMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_TimeBasedVestingAwardMember" substitutionGroup="xbrli:item" />
  <xsd:element name="MarketBasedVestingAwardMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_MarketBasedVestingAwardMember" substitutionGroup="xbrli:item" />
  <xsd:element name="TwoThousandTwentyTwoEquityIncentivePlanMember" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_TwoThousandTwentyTwoEquityIncentivePlanMember" substitutionGroup="xbrli:item" />
  <xsd:element name="PercentageOfTheCommonStockOfAllClassesOutstandingOnPrecedingYear" type="dtr-types:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" id="rgti_PercentageOfTheCommonStockOfAllClassesOutstandingOnPrecedingYear" substitutionGroup="xbrli:item" />
  <xsd:element name="PeriodAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_PeriodAxis" substitutionGroup="xbrldt:dimensionItem" />
  <xsd:element name="PeriodDomain" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_PeriodDomain" substitutionGroup="xbrli:item" />
  <xsd:element name="WeightedAverageSharePriceAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_WeightedAverageSharePriceAxis" substitutionGroup="xbrldt:dimensionItem" />
  <xsd:element name="WeightedAverageSharePriceDomain" type="dtr-types:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" id="rgti_WeightedAverageSharePriceDomain" substitutionGroup="xbrli:item" />
  <xsd:element name="EarnoutLiabilityAbstract." id="rgti_EarnoutLiabilityAbstract." type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DisclosureOfEarnoutLiabilityTextBlock" id="rgti_DisclosureOfEarnoutLiabilityTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PrivateWarrantsMember" id="rgti_PrivateWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DeferredAssetsInConnectionWithWarrantsIssuedToCustomer" id="rgti_DeferredAssetsInConnectionWithWarrantsIssuedToCustomer" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="TimeBasedVestingRestrictedStockUnitsMember" id="rgti_TimeBasedVestingRestrictedStockUnitsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ShareTriggeringEventAxis" id="rgti_ShareTriggeringEventAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ShareTriggeringEventDomain" id="rgti_ShareTriggeringEventDomain" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SharePriceEqualOrExceedsAboveDollarTwoPerShareMember" id="rgti_SharePriceEqualOrExceedsAboveDollarTwoPerShareMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SharePriceEqualOrExceedsAboveDollarFourPerShareMember" id="rgti_SharePriceEqualOrExceedsAboveDollarFourPerShareMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfTradingDaysWithinWhichAwardWillBeVested" id="rgti_NumberOfTradingDaysWithinWhichAwardWillBeVested" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfConsecutiveTradingDaysWithinWhichAwardWillBeVested" id="rgti_NumberOfConsecutiveTradingDaysWithinWhichAwardWillBeVested" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MarketBasedVestingRestrictedStockUnitsMember" id="rgti_MarketBasedVestingRestrictedStockUnitsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PostConversionMember" id="rgti_PostConversionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MeasurementInputSimulatedTradingDaysMember" id="rgti_MeasurementInputSimulatedTradingDaysMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FairValueLiabilitiesLevel3ToLevel1TransfersNumberOfWarrants" id="rgti_FairValueLiabilitiesLevel3ToLevel1TransfersNumberOfWarrants" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="GainLossOnTransfersInOutLevel3FairValueLiability" id="rgti_GainLossOnTransfersInOutLevel3FairValueLiability" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SupernovaAcquisitionMember" id="rgti_SupernovaAcquisitionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SignificantAccountingPolicyPolicyTextBlock" id="rgti_SignificantAccountingPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MacroeconomicConditionsPolicyPolicyTextBlock" id="rgti_MacroeconomicConditionsPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantsOrRightsWarrantsIssuedDuringPeriodUnits" id="rgti_ClassOfWarrantsOrRightsWarrantsIssuedDuringPeriodUnits" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantsVestingPercentage" id="rgti_ClassOfWarrantsVestingPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PurchasesOfPropertyAndEquipmentRecordedInAccountsPayable" id="rgti_PurchasesOfPropertyAndEquipmentRecordedInAccountsPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="RisksAndUncertaintiesPolicyPolicyTextBlock" id="rgti_RisksAndUncertaintiesPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="IncreaseInCommonStockCapitalSharesReservedForFutureIssuance" id="rgti_IncreaseInCommonStockCapitalSharesReservedForFutureIssuance" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingFairValue" id="rgti_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="MaximumValueOfSharesAuthorizedUnderAgreement" id="rgti_MaximumValueOfSharesAuthorizedUnderAgreement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromSaleOfCommonStockFromSalesThroughAtMarketOffering" id="rgti_ProceedsFromSaleOfCommonStockFromSalesThroughAtMarketOffering" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ChangesInStockholdersEquityTextBlock" id="rgti_ChangesInStockholdersEquityTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AtMarketOfferingAgreementMember" id="rgti_AtMarketOfferingAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="GovernmentEntitiesMember" id="rgti_GovernmentEntitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PerShareWeightedAveragePriceOfSharesIssued" id="rgti_PerShareWeightedAveragePriceOfSharesIssued" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="StockIssuanceCosts" id="rgti_StockIssuanceCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="RemainingValueOfSharesAuthorizedUnderAgreement" id="rgti_RemainingValueOfSharesAuthorizedUnderAgreement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtInstrumentFinalPaymentFeePercentage" id="rgti_DebtInstrumentFinalPaymentFeePercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="CustomerGMember" id="rgti_CustomerGMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="GailSanfordMember" id="rgti_GailSanfordMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ShareBasedCompensationPeriodOfAnnualIncreasesInSharesReservedForIssuanceInYears" id="rgti_ShareBasedCompensationPeriodOfAnnualIncreasesInSharesReservedForIssuanceInYears" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="UsTreasurySecuritiesShortTermMember" id="rgti_UsTreasurySecuritiesShortTermMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AvailableForSaleSecurityShortTermMember" id="rgti_AvailableForSaleSecurityShortTermMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UsTreasurySecuritiesLongTermMember" id="rgti_UsTreasurySecuritiesLongTermMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AvailableForSaleSecurityLongTermMember" id="rgti_AvailableForSaleSecurityLongTermMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CollaborativeResearchMaterialsAndSalesOfQuantumComputersMember" id="rgti_CollaborativeResearchMaterialsAndSalesOfQuantumComputersMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SegmentReportingAndRisksAndUncertaintiesAbstract" id="rgti_SegmentReportingAndRisksAndUncertaintiesAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SegmentReportingAndRisksAndUncertaintiesTextBlock" id="rgti_SegmentReportingAndRisksAndUncertaintiesTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SingleReportableSegmentMember" id="rgti_SingleReportableSegmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RentAndFacilities" id="rgti_RentAndFacilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProfessionalServicesAndLegalFees" id="rgti_ProfessionalServicesAndLegalFees" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="CostDirectAndIndirectMaterial" id="rgti_CostDirectAndIndirectMaterial" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PaymentOfTaxWithholdingsOnSellToCoverEquityAwardTransaction" id="rgti_PaymentOfTaxWithholdingsOnSellToCoverEquityAwardTransaction" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ClassOfWarrantOrRightRedemptionPriceOfWarrantsOrRights" id="rgti_ClassOfWarrantOrRightRedemptionPriceOfWarrantsOrRights" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsStockPriceTrigger" id="rgti_ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsStockPriceTrigger" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="RedemptionOfWarrantsWhenPricePerShareOfCommonStockEqualsOrExceeds18.00Member" id="rgti_RedemptionOfWarrantsWhenPricePerShareOfCommonStockEqualsOrExceeds18.00Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RedemptionOfWarrantsWhenPricePerShareOfCommonStockEqualsOrExceeds10.00Member" id="rgti_RedemptionOfWarrantsWhenPricePerShareOfCommonStockEqualsOrExceeds10.00Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="QuantaComputerIncMember" id="rgti_QuantaComputerIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="QuantaComputerCollaborationAgreementMemberMember" id="rgti_QuantaComputerCollaborationAgreementMemberMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CollaborativeArrangementDisclosureAbstract" id="rgti_CollaborativeArrangementDisclosureAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MichaelCliftonMember" id="rgti_MichaelCliftonMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AlissaFitzgeraldMember" id="rgti_AlissaFitzgeraldMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RayJohnsonMember" id="rgti_RayJohnsonMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AdjustmentToAdditionalPaidInCapitalEarnoutLiabilityUponVestingOfSponsorShares" id="rgti_AdjustmentToAdditionalPaidInCapitalEarnoutLiabilityUponVestingOfSponsorShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ClassOfWarrantOrRightsNumberOfWarrantsExercised" id="rgti_ClassOfWarrantOrRightsNumberOfWarrantsExercised" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="TradingArrangementForSaleOfSharesMember" id="rgti_TradingArrangementForSaleOfSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TradingArrangementForSaleOfWarrantsMember" id="rgti_TradingArrangementForSaleOfWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TradingArrangementForSaleOfSharesAt15OrHigherMember" id="rgti_TradingArrangementForSaleOfSharesAt15OrHigherMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TradingArrangementForSaleOfSharesAt20OrHigherMember" id="rgti_TradingArrangementForSaleOfSharesAt20OrHigherMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TradingArrangementForSaleOfSharesAt30OrHigherMember" id="rgti_TradingArrangementForSaleOfSharesAt30OrHigherMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AdjustmentToAdditionalPaidInCapitalReclassificationOfDerivativeLiabilitiesUponExerciseOfPublicWarrants" id="rgti_AdjustmentToAdditionalPaidInCapitalReclassificationOfDerivativeLiabilitiesUponExerciseOfPublicWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromTaxWithholdingsOnSellToCoverEquityAwardTransactions" id="rgti_ProceedsFromTaxWithholdingsOnSellToCoverEquityAwardTransactions" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SaleOfStockLockOutProvisionTerm" id="rgti_SaleOfStockLockOutProvisionTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DebtSecuritiesAvailableForSaleNumberOfLongTermSecurities" id="rgti_DebtSecuritiesAvailableForSaleNumberOfLongTermSecurities" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="ProceedsFromUnderlyingWarrantDerivativeLiabilitiesSettled" id="rgti_ProceedsFromUnderlyingWarrantDerivativeLiabilitiesSettled" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SalesAgentCommissionPaidAsPercentageOfGrossProceedsOfSharesSold" id="rgti_SalesAgentCommissionPaidAsPercentageOfGrossProceedsOfSharesSold" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="OpenMarketSalesAgreementMember" id="rgti_OpenMarketSalesAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ThomasIannottiMember" id="rgti_ThomasIannottiMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CommonStockTradingPlanMember" id="rgti_CommonStockTradingPlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="RestrictedStockUnitsTradingPlanMember" id="rgti_RestrictedStockUnitsTradingPlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CollaborativeAgreementOwnershipPercentage" id="rgti_CollaborativeAgreementOwnershipPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AdjustmentToAdditionalPaidInCapitalEarnoutLiabilityUponVestingOfSponsorRedemptionBasedShares" id="rgti_AdjustmentToAdditionalPaidInCapitalEarnoutLiabilityUponVestingOfSponsorRedemptionBasedShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SponsorRedemptionBasedVestingSharesMember" id="rgti_SponsorRedemptionBasedVestingSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PromoteSponsorVestingSharesMember" id="rgti_PromoteSponsorVestingSharesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ReclassificationOfEarnoutLiabilitiesToAdditionalPaidInCapitalForVestingOfSponsorVestingShares" id="rgti_ReclassificationOfEarnoutLiabilitiesToAdditionalPaidInCapitalForVestingOfSponsorVestingShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtSecuritiesAvailableForSaleNumberOfSecuritiesSold" id="rgti_DebtSecuritiesAvailableForSaleNumberOfSecuritiesSold" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfReportableSegmentsNotDisclosedFlag" id="rgti_NumberOfReportableSegmentsNotDisclosedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
</xsd:schema>
