United States securities and exchange commission logo August 17, 2022 Chad Rigetti Chief Executive Officer Rigetti Computing, Inc. 775 Heinz Avenue Berkeley, CA 94710 Re: Rigetti Computing, Inc. Registration Statement on Form S-1 Filed August 12, 2022 File No. 333-266810 Dear Mr. Rigetti: We have limited our review of your registration statement to those issues we have addressed in our comments. In some of our comments, we may ask you to provide us with information so we may better understand your disclosure. Please respond to this letter by amending your registration statement and providing the requested information. If you do not believe our comments apply to your facts and circumstances or do not believe an amendment is appropriate, please tell us why in your response. After reviewing any amendment to your registration statement and the information you provide in response to these comments, we may have additional comments. Form S-1 filed August 12, 2022 General 1. We note that Ampere is not obligated to make the additional $5 million payment for the second tranche of 500,000 shares if Ampere's capital stock is not listed by the second anniversary of the warrant subscription agreement. Generally, securities issued in a private transaction may not be registered for resale until after the private placement is completed. In this regard, we note that Ampere is not irrevocably bound to purchase the subject securities because whether Ampere chooses to list its capital stock is a condition within Ampere's control. Please refer to Question 134.01 of our Securities Act Sections Compliance and Disclosure Interpretations for guidance, and provide us with your analysis of how the registration of these shares is appropriate. Chad Rigetti FirstName LastNameChad Rigetti Computing, Inc. Rigetti Comapany August 17, NameRigetti 2022 Computing, Inc. August Page 2 17, 2022 Page 2 FirstName LastName Selling Stockholder, page 144 2. Revise to identify the natural person or persons who exercise the voting and/or dispositive powers with respect to the securities owned by Ampere Computing LLC. Exhibits 3. Please file your collaboration agreement with Ampere and revise your prospectus to summarize the material terms of this agreement. See Item 601(b)(10)(ii)(A) of Regulation S-K. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Refer to Rules 460 and 461 regarding requests for acceleration. Please allow adequate time for us to review any amendment prior to the requested effective date of the registration statement. Please contact Mitchell Austin, Staff Attorney, at (202) 551-3574 or, in his absence, Joshua Shainess, Legal Branch Chief, at (202) 551-7951 with any questions. Sincerely, Division of Corporation Finance Office of Technology